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Index > Protein center > BHMT(Gene name) > Human
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  • BHMT (Gene name),
  • Betaine--homocysteine S-methyltransferase 1 (Protein name ),  BHMT1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BHMT;
    Protein name:
    Betaine--homocysteine S-methyltransferase 1;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    406
    Sequence:
    50:
    MPPVGGKKAK | KGILERLNAG | EIVIGDGGFV | FALEKRGYVK | AGPWTPEAAV | 
    100:
    EHPEAVRQLH | REFLRAGSNV | MQTFTFYASE | DKLENRGNYV | LEKISGQEVN | 
    150:
    EAACDIARQV | ADEGDALVAG | GVSQTPSYLS | CKSETEVKKV | FLQQLEVFMK | 
    200:
    KNVDFLIAEY | FEHVEEAVWA | VETLIASGKP | VAATMCIGPE | GDLHGVPPGE | 
    250:
    CAVRLVKAGA | SIIGVNCHFD | PTISLKTVKL | MKEGLEAARL | KAHLMSQPLA | 
    300:
    YHTPDCNKQG | FIDLPEFPFG | LEPRVATRWD | IQKYAREAYN | LGVRYIGGCC | 
    350:
    GFEPYHIRAI | AEELAPERGF | LPPASEKHGS | WGSGLDMHTK | PWVRARARKE | 
    400:
    YWENLRIASG | RPYNPSMSKP | DGWGVTKGTA | ELMQQKEATT | EQQLKELFEK | 
    406:
    QKFKSQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    SMR:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    E13443b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    E13443m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    E13443p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    E13443r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    E13443h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    U13443b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    U13443h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    U13443m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    U13443p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    U13443r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Polyclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Polyclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    P13443Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    P13443Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Cat.:
    P13443Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Monoclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Monoclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Monoclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Monoclonal Antibody for Human Betaine--homocysteine S-methyltransferase 1
    Protein for Human Betaine--homocysteine S-methyltransferase 1
    Protein for Human Betaine--homocysteine S-methyltransferase 1
    Protein for Human Betaine--homocysteine S-methyltransferase 1
    Protein for Human Betaine--homocysteine S-methyltransferase 1
    Protein for Human Betaine--homocysteine S-methyltransferase 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase."
      Garrow T.A.
      J. Biol. Chem.271:22831-22838(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLN-239
      tissue: Liver.
    2. 2.
      "Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene."
      Park E.I. , Garrow T.A.
      J. Biol. Chem.274:7816-7824(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Lung.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    4. 4.
      "Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene."
      Sunden S.L.F. , Renduchintala M.S. , Park E.I. , Miklasz S.D. , Garrow T.A.
      Arch. Biochem. Biophys.345:171-174(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Human betaine-homocysteine methyltransferase is a zinc metalloenzyme."
      Millian N.S. , Garrow T.A.
      Arch. Biochem. Biophys.356:93-98(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION;ZINC-BINDING
      tissue: Liver.
    6. 6.
      "Betaine-homocysteine methyltransferase: zinc in a distorted barrel."
      Evans J.C. , Huddler D.P. , Jiracek J. , Castro C. , Millian N.S. , Garrow T.A. , Ludwig M.L.
      Structure10:1159-1171(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS);SUBUNIT
    7. 7.
      "Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease."
      Weisberg I.S. , Park E. , Ballman K.V. , Berger P. , Nunn M. , Suh D.S. , Breksa A.P. , Garrow T.A. , Rozen R.
      Atherosclerosis167:205-214(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLN-239
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